Viscous Gels to Help with Healing

Do you or does someone you know have a wound that hurts or hasn’t healed? Perhaps a problem in their esophagus due to a condition, or throat after a tonsillectomy, or the “other end” after a hemorrhoidectomy? Our compounding pharmacy can prepare medications that adhere to the mucosal lining or an open wound, to cover, protect, and soothe the area and allow it to heal.

We can compound medications for problems like esophagitis, or an area where a fistula or hemorrhoid was treated, or a non-healing wound (such as a burn, a chronic venous leg ulcer, or a rectal problem like chronic
radiation-induced proctitis) using a base that has a characteristic known as thermal reversibility. That is, it’s a liquid when refrigerated or at room temperature, but when it is warmed to body temperature, it become a gel and adheres to the mucous membranes for a prolonged period of time, keeping the medication where it’s needed, and decreasing the required dosage and also the risk of side effects.

This gel base, Poloxamer 407 which is also known as Pluronic® F127, has been shown to be compatible with various types of medications and can be administered via various routes, including oral, nasal, topical, or rectal.

If you have a problem that has not responded to commercially available medications or other types of therapy, contact our compounding pharmacist. We will work with you and your doctor to prepare a medication that meets your unique needs. Your questions are always welcome.

References:
Pharmaceutics. 2018 Sep; 10(3): 159
Int J Pharm Compd. 2019 Sep-Oct;23(5):380-381.

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